Background: Femtosecond-laser assisted clear cornea cataract surgery may hold promise in safer and more\neffective procedures. We decided to perform a comparative study to standard manual incision phacoemulsification\nsurgery.\nMethods: This is a single-center, single-intervention, and prospective comparative data evaluation of 133\nconsecutive cases subjected to cataract surgery. Group-A (Phaco), manual capsulorhexis & ultrasound\nphacoemulsification (n = 66); Group-B femtosecond-laser assisted capsulorhexis and lens fragmentation (n = 67),\nemploying the LenSx laser (Alcon Surgical, Ft. Worth, TX). All cases were evaluated for refraction, visual acuity,\nkeratometry, tomography, pachymetry, endothelial cell counts, intraocular pressure, and type of intraocular lens\n(IOL) implanted. The groups were matched for age, gender, pre-operative vision metrics, and cataract grade, and\nwere followed up to 1 year.\nResults: In group-A post-operative uncorrected distance visual acuity (UDVA) was 20/20 or better in 61.5 % and\n20/25 or better in 78.5 % of the eyes. The femtosecond laser group-B had improved outcomes (p = 0.075 and p = 0.\n042, respectively): post-operative UDVA was 20/20 or better in 62.7 % of the eyes and 20/25 or better in 85.1 %.\nLinear regression scatterplots of achieved versus attempted spherical equivalent had excellent regression\ncoefficients (r2 = 0.983 in group-A and 0.979 in group-B). There were 75.2 % cases in group-A and 80.6 % in group-B\n(p = 0.8732) within Ã?±0.50 D of targeted refractive equivalent. Slight trend of under-correction was noted in group-A.\nAverage residual manifest cylinder in the toric subgroup-A was -0.50 D (95 % Limit-of-Agreement (LoA) = -0.78 D),\nand in toric subgroup-B -0.45 D (LoA = -0.45 D).\nConclusions: Mean spherical equivalent refraction and visual acuity are comparable with laser cataract surgery\ncompared with manual capsulorhexis & ultrasound phacoemulsification. Improved astigmatism correction may be\namong the benefits of femtosecond laserââ?¬â??assisted cataract surgery. Transient corneal edema may be a first day\ntransient disadvantage in femtosecond laserââ?¬â??assisted cataract surgery.
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